The Real Madrid forward returns to Old Trafford for the first time since leaving the Red Devils, when the two sides square off in the second leg of their Champions League last-16 clash on Tuesday.
"It would be a big ask for many reasons," Vidic told The Sun. "I would love to see Cristiano here; I could see it.
"He is a United supporter. Even though he left he still follows United and still misses the club and the environment here."
United host Madrid on Tuesday night at Old Trafford.