Nigel Clough's side have only amassed six points from a possible 18 and haven't won a league match in their last five attempts.
While the records show that they have not been beaten at home in five encounters, three of those have ended in draws.
In contrast to Derby, Ian Holloway's Palace are still in contention for promotion. The Eagles have picked up 20 points from a possible 51 on the road up until this point.
Possible starting lineups:
Derby: Legzdins; Brayford, Keogh, Buxton, Bryson; Coutts, Hendrick, Jacobs, Davies; Ward, Sammon
Palace: Speroni; Delaney, Ramage, Richards, Parr; Bolasie, Dikgacoi, Jedinak, Zaha; Phillips, Murray