Benitez has several fitness issues to contend with before naming his side, with Petr Cech likely to miss out with a broken finger while Demba Ba suffered a broken nose in last week's 3-2 loss to Newcastle United.
Wigan have dropped into the Premier League relegation zone in recent weeks and they will be hoping to record their first victory in the league since the turn of the year.
Wigan Athletic: DWLWDD
Possible starting lineups
Chelsea: Turbull; Ivanovic, Bertrand, Cahill, Terry; Hazard, Ramires, Lampard, Mata, Oscar; Torres
Wigan Athletic: Al Habsi; Caldwell, Stam, Figueroa, Scharner; Maloney, McArthur, Espinoza, McCarthy, Beausejour; Di Santo
Sports Mole says: 3-1