The Clarets, who are unbeaten in their last 15 league games, have a 10-point cushion between themselves and third-placed Derby County in the standings.
A win tomorrow night would see Sean Dyche's side take a step closer to sealing automatic promotion to the Premier League.
At the other end of the table, Doncaster are in need of the points as they battle against relegation.
Rovers are currently eight points clear of danger thanks to Saturday's 1-0 win over Sheffield Wednesday, though a defeat tomorrow night could drag them right back into a scrap for survival.
Possible starting lineups
Burnley: Heaton; Baird, Mee, Jones, Duff; Shackell, Arfield, Marney, Vokes; Barnes, Stanislas
Doncaster: Johnstone; Coppinger, Husband, Meite, Quinn; Keegan, Wellens, Cotterill, Duffy; Brown, Sharp
Sports Mole says: 3-0