Elche boss Fran Escriba will be hopeful that his team can improve on their performance last season after they avoided relegation by one point.
Los Franjiverdes have been handed the toughest of starts, but with the Catalan giants missing several first-team players, it could give Elche the opportunity to give a good account of themselves at Camp Nou.
On-loan Chelsea midfielder Mario Pasalic could be handed a debut in the centre of midfield.
Possible starting lineups
Barcelona: Bravo; Pique, Dani Alves, Jordi Alba, Mascherano; Xavi, Iniesta, Rakitic, Busquets; Rafinha, Messi
Elche: Herrera; Suarez, Roco, Lomban, Albacar; Niguez, Gonzalez, Rodrigues, Mosquera, Pasalic; Coro
Sports Mole says: 5-0