Scotland winger Sean Maitland has been ruled out of Saturday's Six Nations clash with England due to injury.
The 25-year-old suffered concussion as well as damage to his right leg during last weekend's 28-6 defeat to Ireland in Dublin.
He will now sit out the match against old rivals England at Murrayfield as the Scots look for their first win of the tournament.
Scotland have failed to beat England in any of their last six meetings.