The Grand Slam is Ireland's third in its history, and England's loss is just the second time in history - after France in 1981 - that a Grand Slam was confirmed for the visitors at the home of English rugby.
Ireland were off the mark after just six minutes as Anthony Watson, challenged by Rob Kearney, spilled a high kick sent into the snow by Jonathan Sexton and Ringrose dived on the loose ball as it bounced over the try line.
Three minutes later, England earned their first penalty of the day after Keith Earls went off feet at a ruck on the Ireland 22, but with Owen Farrell kicking to the corner, Ireland forced a turnover at the maul.
Stander increased Ireland's lead on 24 minutes, touching the ball down at the base of a post, but Daly responded for England, capitalising on a fine diagonal kick into the in-goal area from Farrell.
Stockdale came up with a critical score on the stroke of half-time to secure a 21-5 lead and set a record with his eighth try of the championship, chipping over the defence and touching down ahead of the deadball line.
After the break, Conor Murray extended Ireland's lead with a penalty before Daly scored a second try and May then added another for England after the 80 minutes, though none of the home side's tries were converted in a largely lacklustre display.