The Irish singer, who rose to fame as part of a five-piece boy band on The X Factor, watched Tuesday night's goalless draw at the Vicente Calderon.
The club's Twitter account posted a photo of the Irishman with Cerezo holding an Atletico shirt with 'One Direction' printed on the back. A message read: "Thanks @NiallOfficial for the visit! It's been a luxury to have a @onedirection member at the Calderón! ;) #UCL."
Twenty-year-old Horan has met a number of famous footballers, including Barcelona star Lionel Messi and Brazil international Neymar.