Later this month, the Dragons face two fixtures in Asia - including against China on March 22 - and Giggs has opted to including a number of newcomers in his first squad.
Preston North End duo Chris Maxwell and Billy Bodin, Ipswich Town goalkeeper Michael Crowe, Swansea City full-back Connor Roberts and Brentford centre-back Chris Mepham could all make their first appearances for the senior side.
Wales will play either Uruguay or Czech Republic in the second fixture in China, regardless of whether they are successful against the tournament hosts.
Goalkeepers: Wayne Hennessey, Chris Maxwell, Michael Crowe
Defenders: Ashley Williams, James Chester, Ben Davies, Chris Gunter, Neil Taylor, Declan John, Ryan Hedges, Connor Roberts, Ethan Ampadu, Chris Mepham, Tom Lockyer
Midfielders: Joe Allen, Joe Ledley, Lee Evans, Andy King, Tom Lawrence, Harry Wilson, Marley Watkins,
Strikers: Gareth Bale, Sam Vokes, Ben Woodburn, Tom Bradshaw, Billy Bodin