Off the back of a third-place finish last time out, the away side will head into the upcoming campaign with renewed optimism, while their visitors seek to improve on a sixth-place finish.
Feyenoord closed out their preparation for the new season on the back foot as they suffered a 2-1 defeat against Espanyol on Sunday at De Kuip.
Arne Slot's men fell behind to Roberto Torres's opener on the half-hour mark, and after managing to draw level through Cole Bassett two minutes from time, Kike Barja popped up with a late winner in Rotterdam.
De Stadionclub have now lost four of their six pre-season friendlies and will be looking to get themselves back on track as the real action commences.
Awaiting them next is the task of facing off against an opposing side who have not come out on top in any of the previous six meetings between the teams since 2019.
Having won six of eight domestic matches on the road since the turn of the year, Sunday's visitors will fancy themselves to secure another feather in the cap away from home.
Vitesse suffered a narrow 2-1 defeat at the hands of Greek outfit Atromitos in their final warm-up encounter on Saturday evening.
Consequently, the Arnhem-based side have now failed to win any of their last four outings, while their last seven involvements have yielded just one victory.
Sunday's hosts follow up this weekend's clash with a contest against Excelsior next Friday, while their visitors await the challenge of Heerenveen the following day.
Orkun Kokcu is not expected to play any part for Feyenoord this weekend, as the 21-year-old midfielder is ruled out through an ankle injury.
New arrival Javairo Dilrosun is in line to make his official debut for the away side, and he will be looking to make an impression on day one.
Mats Wieffer continues his extended spell on the sidelines through a syndesmotic ligament tear which has kept him out of action since February.
Lois Openda was on target in the most recent meeting between Sunday's opponents, and the Belgian will be looking to deliver the goods once again.
Vitesse possible starting lineup:
Houwen; Arcus, Ferro, Flamingo, Manhoef, Wittek; Bero, Meulensteen, Tronstad; Frederiksen, Sankoh
Feyenoord possible starting lineup:
Bijlow; Pedersen, Geertruida, Senesi, Rasmussen; Timber, Aursnes, Szymanski; Dilrosun, Danilo, Idrissi
We say: Vitesse 1-2 Feyenoord
The teams boast a huge pool of attacking talent on display, so we are expecting goals at both ends. That said, we are backing Feyenoord to just about come away with all three points at the end of the 90 minutes here.
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