Shelvey only joined the club from Swansea City in January, but with usual skipper Fabricio Coloccini currently sidelined, the England international has taken on the armband this evening.
The Magpies have made four changes to the side that was beaten by Chelsea in their last competitive match, which came 18 days ago.
Marko Arnautovic, who scored a brace at the weekend to make it six goals in his last eight league appearances at the Britannia Stadium, forms a trio alongside Xherdan Shaqiri and Ibrahim Afellay just behind the striker.
Stoke City: Butland; Bardsley, Cameron, Wollscheid, Pieters; Whelan, Imbula, Shaqiri, Afellay, Arnautovic; Walters
Subs: Haugaard, Muniesa, Ireland, Joselu, Diouf, Crouch, Bojan
Newcastle United: Elliot; Janmaat, Taylor, Lascelles, Dummett; Shelvey, Colback, Sissoko, Wijnaldum, Gouffran; Mitrovic
Subs: Darlow, Sterry, Saivet, Aarons, Perez, Riviere, Doumbia
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