Both sides sit dangerously close to the relegation zone and a defeat for either team could see them slip into the bottom three.
Wednesday come into the game in the worse form with three losses in their last four matches, while Barnsley will be in confident mood thanks to two wins in a row.
Sheff Weds: DWLLWL
Sheff Weds: Kirkland; Buxton, R Johnson, Gardner, Llera; Antonio, Helan, Pugh, Olofinjana; Prutton,, Lita
Barnsley: Steele; Wiseman, Cranie, Kennedy, Hassell; O'Brien Perkins, Mellis, Scotland; Etuhu, Dagnall
Sports Mole says: 2-2