Juventus can extend their winning run in Serie A to seven games on Saturday if they grab all three points over Sassuolo, who are currently rooted to the bottom of the league table.
Prior to the international break, Massimiliano Allegri's side managed to overcome rivals Roma with a 3-2 victory, courtesy of goals from Carlos Tevez and Leonardo Bonucci.
With that, the Old Lady pushed a three-point gap between themselves and second-placed Roma at the top of the standings, while Sassuolo are still searching for their first win in Serie A this season.
Taking three points out of a possible 18 has left Eusebio Di Francesco's side at the bottom of the table, but with a victory they could possibly climb out of the relegation places.
Last season, Juventus secured emphatic wins over Sassuolo both home and away with a 4-0 victory and 3-1 triumph.
The home side are likely to start Simone Zaza and Nicola Sansone up front, while Fernando Llorente and Carlos Tevez are likely to provide the goal threat for Juventus.
Recent form
Sassuolo: DLDDLL
Juventus: WWWWWW
Possible starting lineups
Sassuolo: Consigli; Vrsaljko, Cannavaro, Antei, Longhi; Biondini, Magnanelli, Taider; Berardi, Zaza, Sansone
Juventus: Buffon; Ogbonna, Bonucci, Chiellini; Lichtsteiner, Pogba, Pirlo, Marchisio, Evra; Llorente, Tevez
Sports Mole says: 0-3
Danielle Joynson
