Cristiano Ronaldo hit a brace for the European champions, while Gareth Bale was also on the scoresheet as Real Madrid put their La Liga troubles to one side by posting their first ever victory away at Dortmund.
Read how it all unfolded in Sports Mole's minute-by-minute live commentary of the action below.
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BVB: Burki; Piszczek, Sokratis, Toprak, Toljan; Gotze, Sahin, Castro; Philipp, Aubameyang, Yarmolenko
REAL: Navas; Carvajal, Ramos, Varane, Nacho; Kroos, Modric, Casemiro; Isco, Ronaldo, Bale
400 - Cristiano Ronaldo will make his 400th appearance for Real Madrid in all competitions. Myth. pic.twitter.com/fQxkCspjo5— OptaJose (@OptaJose) September 26, 2017