Defender Emmanuel Onariase has had a hernia operation and is therefore a doubtful inclusion.
Captain Jordan Clarke is lacking fitness after a calf issue and so too is fellow defender Harrison McGahey, meaning both could be rested.
Port Vale boss John Askey is likely to make a late call on the fitness of a handful of squad members.
All four players have since returned to training and could feature if they are able to regain fitness in time.
Only defender James Gibbons is completely ruled out due to a knee injury, but is not expected to be a long-term absentee.