At the weekend, reports began to emerge that the Italy and AC Milan legend had agreed to replace Roberto Breda, who left the club after the 1-1 draw with Novara.
Perugia are looking to earn promotion to Serie A through the playoffs, and Nesta admits that he is 'enthusiastic' to take on the position at Stadio Renato Curi.
The 42-year-old said: "It's been a while. I don't remember the last time I was at this stadium. I come here with great enthusiasm.
"This is a real football club. The team are strong and would be with me and any other coach."
Nesta's only previous managerial role came at American side Miami FC.