The possible exit of Henrikh Mkhitaryan as part of a swap deal for Alexis Sanchez has dominated the United transfer news in recent days, and Mourinho admitted that it is a possibility that the Armenia international will leave the club this month.
However, Mourinho suggested that he would actively look to secure a move away for Tuanzebe in order for the 20-year-old to gain more first-team experience due to a lack of chances at Old Trafford.
"I have a squad of 32 players and I want to keep squad of 32 players. Maybe just because I want to make the kid a good player and I'm not giving him the chances I'm giving to Scott McTominay, for example," he told reporters.
"So probably Axel is the only one that I open the door for him to go and play because I believe he is a really good talent and he needs to play. Apart from that, the numbers we have, we are playing Champions League, FA Cup, Premier League, I have to keep the number of players we have."
Any exit for Tuanzebe will only be a temporary one until the end of the season, with Aston Villa understood to be interested in taking the youngster on loan.