First-team regulars Aleksandar Kolarov, Fernando, Fernandinho and Jesus Navas are joined in the selection by youngsters Pablo Maffeo, Tosin Adarabioyo and Angelino, while teenage winger Brandon Barker is again given the chance to impress and Kelechi Iheanacho is chosen to lead the line.
Ousmane Dembele keeps his place after impressing against Manchester United in the Bundesliga side's 4-1 win over the Red Devils, while Adrian Ramos will lead the line in the absence of Pierre-Emerick Aubameyang.
Borussia Dortmund: Burki, Ginter, Sokratis, Bartra, Schmelzer, Rode, Sahin, Mor, Leitner, Ramos, Dembele
Manchester City: Caballero, Maffeo, Adarabioyo, Kolarov, Angelino, Fernando, Fernandinho, Zinchenko, Barker, Iheanacho, Navas
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