The visitors come into this tie fresh off the back of ending their run of seven straight losses as they held on for a 1-1 draw against Perth Glory last time out.
Macarthur saw their three-game winning run come to an end last Friday as they lost 2-1 against Brisbane Roar.
The Bulls were unable to bounce back from that result as they fell to yet another defeat away to Adelaide United last time out.
On the other hand, Newcastle Jets grabbed a 1-1 draw when they hosted fellow strugglers Perth Glory at the McDonald Jones Stadium.
The result brought no change to either side's position in the table, with Craig Deans's men still in 11th place, one point above rock-bottom Melbourne Victory.
However, this was the Jets' first point since February 20, ending their run of seven straight defeats.
Newcastle Jets will now try to build on this result when they meet Macarthur, as moving up from the bottom of the table remains a priority.
Milicic has the luxury of a full strength squad at his disposal, but we expect the 47-year-old to stick to his preferred starting XI.
Matt Derbyshire has hit 10 goals in his last 11 matches, and he will have a huge role to play in attack for the hosts.
Nineteen-year-old Jake Hollman, who was handed just his third start last time out, could keep his place in the starting lineup after putting on a solid shift in attack.
On the other hand, Nigel Boogaard will sit out this tie as he is sidelined with a leg injury.
He is joined on the treatment table by John Koutroumbis, who battles with a knee problem.
Australian-born midfielder Ben Kantarovski could make his return from a long-term calf injury that has kept him out of action since August 2020.
Macarthur possible starting lineup:
Federici; Golec, Milligan, Susnjar; Li Rose, Benat, Genreau, Oar; La Rose, Derbyshire, Hollman
Newcastle Jets possible starting lineup:
Italiano; Millar, Topor-Stanley, Jackson, O'Toole; Ugarkovic, Thurgate; Stamatelopoulos, Najjarine, Yuel; O'Donovan
We say: Macarthur 2-0 Newcastle Jets
Seated fifth in the league table, Macarthur have enjoyed an impressive debut season in the Australian top flight. Considering the current gulf in quality between both sides, we predict the Bulls grab all three points and heap more misery on the floundering Newcastle Jets.