The Merseyside outfit head into the contest with a two-point lead over their Russian opponents and Italian outfit Udinese, while Young Boys occupy the bottom spot in the standings with just three points.
Liverpool boss Brendan Rodgers is expected to ring the changes from the side that drew 1-1 with Newcastle United in the Premier League on Sunday as captain Steven Gerrard and striker Luis Suarez are expected to be rested.
Anzhi: Gabulov; Samba, Chaves, Boussoufa, Agalarov; Shatov, Carcela, Zhirkov, Gabulov; Eto'o, Smolov
Liverpool: Jones; Wisdom, Carragher, Coates, Robinson; Henderson, Shelvey, Assaidi; Downing, Pacheco, Suso
Sports Mole says: 0-2