Die Mannschaft are second in Group D, a point behind Poland, but will be expected to pick up a comfortable three points when they take on minnows Gibraltar at the Estadio Do Algarve in Portugal tomorrow.
Gibraltar, which has a population of just 30,000, are competing in their first qualifying for a major tournament after being given full UEFA membership two years ago.
Understandably, they have been outclassed and have no points and the worst goal difference (-26) of anyone in qualifying.
David Wilson's side conceded 27 total goals in the first half of qualifying - seven more than anyone else - but they aren't scoreless like San Marino.
Their first competitive goal arrived at Hampden Park in their last qualifier when Lee Casciaro equalised against Scotland in the 20th minute. The hosts would go on to win 6-1, but it was a moment to remember for the minnows.
Since then, they took on Croatia in a friendly on Sunday, going down 4-0 in Varazdin.
Recent Euro 2016 qualifying form: LLLLL
Recent form (all competitions): LLLLLL
It will be exactly 11 months since Germany's fourth World Cup triumph in Brazil when they face Gibraltar tomorrow.
They have failed to win five of their nine games since Brazil, with their late defeat to the USA on Wednesday the third time in four friendlies that they have failed to win.
However, they have won back-to-back games without conceding in Euro 2016 qualifying since an iffy start which saw them win just one of three games against Scotland, Poland and the Republic of Ireland.
Qualification for the finals in France next year still seems likely, especially as the top two and the best third-placed finisher will reach the tournament automatically.
Low's side are a point adrift of leaders Poland, level with third-placed Scotland on 10 points and two clear of Ireland in what is a four-horse race in Group D.
Recent Euro 2016 qualifying form: WLDWW
Recent form (all competitions): DWWDWL
Gibraltar possible starting lineup:
Perez; Garcia, Sergeant, Chipolina, Casciaro, Chipolina; Walker, Bardon, Payas, Gosling; Casciaro
Germany possible starting lineup:
Zieler; Rudy, Mustafi, Rudiger, Hector; Gundogan, Schweinsteiger; Herrmann, Ozil, Schurrle; Kruse
Head To Head
The November reverse in Nuremburg was the first ever meeting between the two sides.
We say: Gibraltar 0-6 Germany
Anything but a comprehensive win for the visitors would be a huge shock. Only Georgia scored fewer than Germany against Gibraltar in the first half of qualifying and Low's men will want to make a statement after the surprise late defeat to the States.