The pair will lock horns in the semi-finals of the competition on Tuesday night, and Varane has picked out Hazard and Lukaku as two players that his team will have to keep quiet in order to progress to the final.
"Hazard is a player with great talent, with much pace and big quality. There are no miracle solutions against him. You have to leave him little space," Varane told reporters.
"Lukaku can make it difficult for any team because of his physique. He has good players around him, but we have those too. We can hurt them up front."
France have not reached the final of a World Cup since 2006, when they lost on penalties to Italy.