However, they host a Latics side keen to earn promotion back to the Championship at the first time of asking after a difficult season.
Coventry City can perhaps count themselves lucky not to playing in League Two this term after escaping relegation on the last day of the season.
Victory at Crawley Town in their final game ensured that Tony Mowbray's men avoided the drop, thanks to two goals in the last 17 minutes.
Despite that relegation near miss, there is an air of optimism around the Ricoh Arena, with Mowbray signing a new contract.
That dream could become more realistic should Mowbray get his wish in overhauling the club's scouting setup.
However, Mowbray will be keen to at least maintain City's form from the end of last term, which saw the Sky Blues lose only four of his 14 games in charge.
Recent form: DWDDLW
A fresh start in the boardroom and in the manager's office may be what Wigan are looking for as they try to regain their Championship status.
Malky Mackay's controversial reign in charge of the Latics, which was overshadowed by allegations of racism stemming from his time at Cardiff City, came to an end in April. Chairman Dave Whelan also stepped down, to be replaced by his grandson David Sharpe.
However, their 3-0 defeat at Blackburn Rovers last week will have done little to aid their preparations for possible bid for a top-two position.
Recent form: LDLWLL
Coventry could offer a debut to Bryn Morris, who joined on a season-long loan from Middlesbrough this week.
Mowbray may look to keep faith with Armstrong and Reda Johnson in attack, despite drawing 0-0 at Oxford United last Saturday, but has the likes of Marcus Tudgay available should he decide to reshuffle.
Despite defeat at Ewood Park last weekend, Caldwell may well keep faith with a similar lineup, which boasted several new faces.
However, after coming through a trial period, ex-Cardiff City full-back Kevin McNaughton may come into contention for a starting place.
Coventry City possible starting lineup:
Burge, Willis, Ricketts, Johnson, Stokes, Maddison, Vincelot, Fleck, Swanson, Lameiras, Armstrong
Wigan Athletic possible starting lineup:
O'Donnell, James, Perkins, Daniels, Power, McCann, Grigg, Jacobs, Morgan, Junior, Kenny
Head To Head
Given that Wigan have only played in the top four divisions since 1978, is it perhaps not surprising that they have only met Coventry on six previous occasions.
However, in that time, the Sky Blues have mustered just one victory over the Latics when City, then of the old Division One, won an FA Cup third-round replay at Springfield Park in 1991, thanks to a solitary Micky Gynn strike.
The sides have not met since 2005 when Paul Jewell's Wigan – then on their way to the Premier League – won 2-1 at Highfield Road.
We say: Coventry 1-1 Wigan
While Wigan may look to make an early statement to back up their tag as one of the promotion favourites, the bookies expect an improved Coventry from last season. With home advantage, City could provide a stern test for the Latics and a score draw may prove a good bet.