Chelsea are to entertain Manchester City in the fifth round of the FA Cup, while holders Arsenal will host Hull City in a replay of the 2014 final.
Tottenham Hotspur welcome Crystal Palace in a London derby in the next stage of the competition, and a trip to Blackburn Rovers awaits for Liverpool if they defeat West Ham United in a fourth-round replay.
Meanwhile, Manchester United will travel to League One strugglers Shrewsbury Town and Everton will visit Premier League rivals Bournemouth.
Fifth-round draw in full: Chelsea vs. Man City Reading vs. West Brom or Peterborough Watford vs. Leeds Shrewsbury vs. Man Utd Blackburn vs. Liverpool or West Ham Spurs vs. Crystal Palace Arsenal vs. Hull City Bournemouth vs. Everton
All of the games will be played between February 19 and 22.