Wales vs. Switzerland (Saturday, 2.00pm)
Both sides have ambitions of reaching at least the first knockout round in the pan-European competition, but Group A is arguably the most competitive of the lot.
We say: Wales 1-1 Switzerland
Wales are a tough side to beat in competitive fixtures and they also have a good record of keeping clean sheets, keeping out the opposition in three of their last four games.
Switzerland, likewise, have the ability to beat any team and head into this contest on a six-match winning streak.
Group A could well be dominated by draws, with Turkey in a similar boat to Wales and Switzerland, and we can see this fixture in Baku finishing all square.
Denmark vs. Finland (Saturday, 5.00pm)
The Danes will be hoping to rival Belgium for top spot in Group F, although Russia will also fancy their chances of advancing to the knockout stage, and it is set to be a fascinating battle in this particular section.
We say: Denmark 2-0 Finland
Finland are certainly capable of making this an uncomfortable match for Denmark, but we are finding it difficult to look past the Danes on this occasion.
Hjulmand's side have won nine of their last 11 international matches, and they should have too much for a Finland team that will enter the contest off the back of three straight losses.
Belgium vs. Russia (Saturday, 8.00pm)
The Gazprom Arena plays host to Belgium and Russia's first fixture of their respective Euro 2020 campaigns, as the two sides prepare for battle in Group B on Saturday night.
Roberto Martinez's men have their eyes firmly on the prize as the number one ranked nation in the world, while Russia have realistic expectations of a top-two finish in the group.
We say: Belgium 2-0 Russia
A Belgium team with the likes of Hazard and De Bruyne firing on all cylinders would have no problem marching to a comfortable success in this fixture, but Russia may sense an opportunity against the injury-hit Red Devils.
Cherchesov's side have flattered to deceive in recent months, though, and after beating them twice in qualification, we can envisage a third consecutive victory for Belgium to kick off their Euro 2020 dream in perfect fashion.