The Belarusian outfit have triumphed against Lille and Bayern Munich to top Group F after two matches and could go a long way to making the next round with victory over the Spanish outfit.
Valencia, meanwhile, suffered defeat against Bayern Munich in their opening fixture, but secured victory over Lille last time out to move onto three points after two games.
BATE have never beaten Spanish opposition in six attempts, but they can call on experienced goalkeeper Andrei Gorbunov, who has kept 17 clean sheets in his last 31 matches.
The home side have no fresh injury concerns ahead of the clash and could once more call on former Arsenal and Barcelona attacker Alexander Hleb. Meanwhile, Valencia have Adil Rami available, but Pablo Piatti and Sergio Canales remain on the sidelines.
BATE: Gorbunov; Polyakov, Filipenko, Simic, Bordachev; Olekhnovich, Likhtarov, Volodkov; Pavlov, Hleb; Rodionov
Valencia: Guaita; Barragan, Rami, Ruiz, Cissokho; Gago, Costa; Feghouli, Jonas, Guardado; Soldado
Sports Mole says: 1-1