The 24-year-old fills the void left by the suspended Suarez, who picked up his sixth yellow card of the season in the 2-0 win over Malaga last weekend.
Elsewhere, Philippe Coutinho returns to the starting lineup having been cup-tied for the midweek win over Chelsea in the Champions League, taking a place in midfield alongside Ivan Rakitic and Paulinho.
Sabin Merino will lead the attack for Athletic in Catalonia, seeking a first goal in his 13th outing of the campaign - nine of those being from the bench.
Barcelona: Ter Stegen; Sergi Roberto, Pique, Umtiti, Alba; Rakitic, Paulinho, Coutinho; Dembele, Alcacer, Messi
Subs: Cillessen, Iniesta, Digne, Andre Gomes, Aleix Vidal, Yerry Mina, Alena
Athletic Bilbao: Arrizabalaga; Lekue, Nunez, Martinez, Saborit; Benat, San Jose, De Marcos, Garcia, Susaeta; Merino
Subs: Iago Herrerin, Iturraspe, Williams, Etxeita, Aduriz, Vesga, Cordoba
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