Chamberlain impressed from the start in the Three Lions' 5-0 win against Moldova to get their campaign off to flier.
The 19-year-old told The Mirror: "It would be special to face Ukraine; it's always an honour to run out at Wembley.
"I had the honour to do it in a friendly against Belgium, so to be able to do that against Ukraine in a World Cup qualifier would be really good for me."
Chamberlain also shared that he is enjoying the chance to learn from the senior players in the national squad.
He said: "I get endless advice on all sorts of things offensively and attacking from the team.
"That gives me the licence to know they are backing me and have confidence in me to let off the handbrake and do what I can do.
Roy Hodgson's side host Ukraine in their first home qualifier on the road to Brazil 2014, in a re-match from their European Championship clash in June.