James Anderson has not recovered from his shoulder injury in time to be included in the England squad for the first Test against Pakistan on July 14 at Lord's.
The 33-year-old, who is the number one bowler in the world, suffered a reported stress fracture during the third Test against Sri Lanka last month.
There is no place in the 12-man squad for Jos Buttler or Ben Stokes either, but Middlesex seamer Toby Roland-Jones gets his first call-up, while Gary Ballance has been recalled.
"Building on the success of the Test series win against Sri Lanka last month, we have maintained our objective of retaining a balanced squad," said national selector James Whitaker. "With an injury to James Anderson, there is an opportunity for Toby Roland-Jones who has been a consistent performer in the County Championship over the last few years and deserves his chance.
"Gary Ballance is recalled to the Test squad for the first time since the winter series in South Africa and could play his first Test for England in 12 months. He has been in recent form with the bat for Yorkshire in the Championship. Gary is mentally strong and we feel that he will add quality and experience to England's middle-order.
"Pakistan will give us a stiff challenge during this series and we can expect some fantastic cricket from both sides over the next couple of months. The selectors would like to take this opportunity to wish Alastair Cook, Trevor Bayliss and the rest of the squad the best of luck for the series."
England will play four Tests in the series.
Danielle Joynson
