The 26-year-old, who has been hampered with a hamstring injury, has 267 rushing yards in five games so far this season.
The Pittsburgh Steelers head coach told reporters: "They have a top-quality running back in Darren McFadden, and their quarterback is capable of breaking you down with his legs. They have done a lot of that, and have been successful in doing so.
"He's capable of going the distance any time he touches the ball. He proved that against us last year. He went 64 yards on us in the early moments of that game last September.
"You have to have good gap integrity, but the secondary also has to do a good job of coning to the ball and restricting the running lanes. McFadden is just that dangerous."
Oakland host the Steelers later today.