The Broncos currently trail the Kansas City Chiefs at the top of the division by two games and now face a stretch of important games against their rivals, but they will be without head coach John Fox, who is recovering from heart surgery.
Woodyard told the club's official website: "We're back at it after the bye week and ready to start a tough stretch with a lot of division games in front of us. It's really important to get off to a good start against the other AFC West teams. We want to establish that dominance.
"Right now, obviously, we're not first in our division – so that's on our mind. San Diego is a good challenge this week.
"We're on the road, it's just our second division game – and it is against a good team – so we're excited for the opportunity that we've got."
Denver face the San Diego Chargers later today.