The Spaniard looked comfortable during his service game, but Mayer managed to grab an early break to take control of the court.
Despite staying strong on serve, Ferrer was unable to trouble the German and broke back, which allowed Mayer to push on and take a one-set lead.
Ferrer needed to start the second set strongly, but Mayer's dominance continued and the Spaniard dropped 4-1.
However, the fourth seed managed to bounce back and get three quick successive games on the board.
Despite signs of a comeback from Ferrer, Mayer was able to remain composed and wrap up the match.