Questions over the future of the 25-year-old have been raised following the defender's call-up into the England squad, which has prompted the Premier League outfit to tie down the centre-back to a new deal at the club.
"If we do a deal there will be no-one more pleased than myself," said Pulis. "We took Ryan as a young lad and he has grown with the football club, he has been fantastic for us, and the club has been fantastic for him as well.
"Obviously any new deal has to be right for the club and for Ryan, and fingers crossed we can get it done, and we push on from there. We're hoping and praying Ryan will be a Stoke player for the rest of his life."
Shawcross moved to Stoke in 2008 after spending his youth career at Manchester United.