Dawson, who has been sidelined with an Achilles injury, is joined by Younes Kaboul in the centre of defence following injuries to Williams Gallas and Ledley King.
Landon Donovan starts for Everton after his loan move from LA Galaxy, while Victor Anichebe is partnered up front with Louis Saha.
Tottenham Hotspur: Friedel; Walker, Dawson, Kaboul, Assou-Ekotto; Bale, Lennon, Livermore, Modric, Bale, Van der Vaart, Adebayor
Subs: Cudicini, Bassong, Rose, Kranjcar, Pienaar, Defoe, Pavlyuchenko
Everton: Howard; Neville, Heitinga, Distin, Baines; Bilyaletdinov, Fellaini, Donovan, Cahill; Anichebe, Saha
Subs: Mucha, Drenthe, Straqualursi, McFadden, Gueye, Velios, Duffy