AVB said that he is aware of the talent of Van Wolfswinkel having seen him play for Sporting Lisbon, and expects his defence to be kept on their toes.
"Norwich did some strong activity in the transfer window and they look good this year," Villas-Boas told Sky Sports News. "I know Van Wolfswinkel well from seeing him in the Portuguese league.
"He is a very agile player. He is very strong in the air. He has wonderful years in Dutch football and deservedly arrives to the Premier League now too.
"He offers great mobility and great positional sense and he is someone our central defenders have to be aware of."
Spurs are currently sixth in the Premier League with two wins and a defeat from their opening three games.