Liverpool vs. Watford (Saturday, 12.30pm)
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With 16 places and 47 points separating them in the Premier League table, Liverpool and Watford resume top-flight action with Saturday's lunchtime kickoff at Anfield.
The second-placed Reds find themselves just one point behind Manchester City at the summit, while Roy Hodgson's side are three points adrift of safety in 18th.
We say: Liverpool 3-0 Watford
Losing creator-in-chief Alexander-Arnold - even for an expected short amount of time - is a massive blow for this Liverpool side, but Klopp will still expect his XI to break down their opponents with ease at Anfield.
Kicking off a daunting April with a routine three points is a must for the Reds, and we can only envisage the hosts bringing Watford crashing back down to earth with a straightforward success.
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> How Liverpool could line up against Watford
> Liverpool injury, suspension list vs. Watford
> Roberto Firmino's record vs. Watford
Brighton vs. Norwich (Saturday, 3.00pm)
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Brighton & Hove Albion will endeavour to snap an alarming six-game losing run in the Premier League when Norwich City visit the Amex Stadium on Saturday afternoon.
The Seagulls have slipped down to 13th place in the table amid their streak of defeats, while Dean Smith's side remain rock bottom of the pile as the Championship looms.
We say: Brighton & Hove Albion 0-0 Norwich City
The international break came at an ideal time for both managers, but it is still extremely difficult to envisage where the goals might come from in both ranks, so fans should not expect fireworks at the Amex.
In our opinion, this battle has a goalless draw written all over it, with neither shot-shy attack capable of causing their opponents' defence any serious problems.
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Burnley vs. Man City (Saturday, 3.00pm)
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Manchester City will be bidding to return to winning ways in the Premier League when they travel to relegation-threatened Burnley on Saturday afternoon.
The Citizens are currently one point clear of second-placed Liverpool at the top of the table, while Burnley occupy 19th, four points behind 17th-placed Everton heading into this weekend's fixtures.
We say: Burnley 0-2 Manchester City
Burnley will be competitive against Man City, but it is very difficult to imagine anything other than an away victory in this match. The Citizens know that they cannot afford to slip up due to the presence of Liverpool, and Guardiola's side should win this game relatively comfortably.
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> How Manchester City could line up against Burnley
> Man City injury, suspension list vs. Burnley
Chelsea vs. Brentford (Saturday, 3.00pm)
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Seeking a seventh win on the bounce in all competitions, Chelsea resume Premier League action with the visit of Brentford to Stamford Bridge on Saturday afternoon for a West London derby.
The Blues progressed in the FA Cup with a 2-0 win over Middlesbrough before the international break, while the Bees most recently lost 2-1 to Leicester City.
We say: Chelsea 2-0 Brentford
Chelsea will most likely look to wrap up third place as soon as possible in order to focus on shots at silverware in the FA Cup and Champions League, so expect a ruthless showing from Tuchel's in-form side here.
Eriksen's return and strong international period will at least give Brentford a bit more of a creative spark, but Chelsea should still have no problems recording another straightforward victory.
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> How Chelsea could line up against Brentford
> Chelsea injury, suspension list vs. Brentford
Leeds vs. Southampton (Saturday, 3.00pm)
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Seeking to continue their climb away from the drop zone, Leeds United return to Premier League action following the international break with Saturday afternoon's clash against Southampton at Elland Road.
The Whites produced an astounding comeback to beat Wolverhampton Wanderers 3-2 last time out, while Ralph Hasenhuttl's side went down 2-1 to Watford.
We say: Leeds United 2-2 Southampton
A two-week period with no Premier League action may be just the tonic that Southampton needed to recover from their abysmal streak, and Leeds are yet to find the optimal defensive formula under Marsch.
Confidence will be through the roof in the Elland Road ranks following the five-goal thriller at Molineux, but a refreshed Southampton can take advantage of the hosts' ongoing fitness woes to take a point home from an entertaining clash.
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Wolves vs. Aston Villa (Saturday, 3.00pm)
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Having both entered the international break on the back of home defeats, Wolverhampton Wanderers and Aston Villa will aim to bounce back in Saturday's Premier League contest at Molineux.
Bruno Lage's side went down 3-2 to Leeds United in a classic last time out, while the Lions suffered a 1-0 loss to Arsenal in front of their own supporters.
We say: Wolverhampton Wanderers 0-1 Aston Villa
Jimenez and Neves's absences coupled with Neto's fitness woes and an underwhelming spell of form does not spell optimism for Wolves here, but Villa did not enter the international break in glittering form either.
However, Gerrard has plenty of choice when it comes to freshening up his attack and is working with a much fitter squad than Lage, so we can picture Villa returning to winning ways as Wolves' continental aspirations take yet another hit.
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Man Utd vs. Leicester (Saturday, 5.30pm)
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Manchester United will be bidding to give their top-four hopes a boost when they welcome Leicester City to Old Trafford in the Premier League on Saturday evening.
The Red Devils are currently sixth in the table, four points behind fourth-placed Arsenal, who have a game in hand, while Leicester sit 10th, 14 points behind their opponents this weekend.
We say: Manchester United 2-1 Leicester City
There is no downplaying the importance of this match to Man United; it is a must-win fixture for the Red Devils in their battle to secure a top-four spot, and we are expecting the home side to triumph. Leicester have enough quality to find the back of the net, but we are backing Rangnick's team to edge a tight contest.
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