The Italian has been stubborn in his view that rivals Manchester United are favourites for the title and claims that will still be the case even if City win the "derby of all derbies" on Monday night.
"Even if we win this game, I think they are favourites," Mancini told Sky Sports News.
"I think that they have more chance than us because we play a derby on Monday and then we play against Newcastle - which will be a tough game.
"After us, United will play against Swansea and Sunderland - I think for them that will be two easy games."
Mancini also revealed that he has a fully-fit squad to choose from for the fixture.