Real Betis and Sevilla have shared the spoils with an entertaining 1-1 draw in the Seville derby.
There was nothing Barriga could do for Sevilla's opener as Benat Exteberria curled his free kick into the top corner on 25 minutes.
The goalkeeper continued to frustrate the opposition as Frederico Fazio saw his header tipped over the bar.
Sevilla drew level against the run of play five minutes before half time when Negredo rose unmarked to plant his header in the net from Jesus Navas' cross.
The visitors were reduced to 10 men with 20 minutes to play as Fazio was dismissed for an innocuous-looking obstruction on Roque Santa Cruz.
Exteberria nearly gave Sevilla the lead in the final 10 minutes, but he flashed his shot the wrong side of the post.