Chamberlain caught the eye in that role last season in a Champions League match against AC Milan, and believes that he can help to cushion the blow of Alex Song's departure to Barcelona.
He said: "Alex Song was a great player for us and he was a big player, but we've got a strong enough squad. I'm definitely confident of that and I'm definitely confident of filling Alex's role.
"Arsene Wenger has been pushing more this season to try my hand in a more central position.
"If I can prove I can play in that position as well then that will help me and my career at Arsenal"
The 19-year-old has been named in Arsenal's squad to play Stoke City on Sunday, August 26.