Fitzpatrick was given his first big shot in the NFL by Buffalo, but was cut from their side before the start of the 2013-14 campaign, with the back now stating that the coming fixture will be a special one.
"There's definitely no hard feelings with the way that it went down," Fitzpatrick told reporters.
"I think the little added extra whatever it is I'm gonna feel in this game is more so because of the guys I'm playing against, and just having so many good buddies.
"That's what's gonna give me that extra fuel, that extra competitiveness in this game."
The Texans have notched two victories and one defeat in their opening three games of the new season.