Former world number one Andy Murray is drawn to face Lucas Pouille in the opening round of the Cincinnati Open.
The former number one opted to miss this week's Rogers Cup after reaching the quarter-finals of the Citi Open, but the 31-year-old will return with a showdown against the world number 18.
Should Murray come through his opening two matches, Roger Federer could await the Scot in the third round as the Swiss competes for the first time since losing in the last eight at Wimbledon.
British number one Kyle Edmund will go up against American MacKenzie McDonald in the first round, with Rafael Nadal a potential third-round opponent.
Cameron Norrie must come through qualifying in order to secure a place in the main draw, with Marius Copil awaiting the left-hander in the first round.
Johanna Konta will face Aryna Sabalenka in the first round of the women's draw.