The Swiss, who will be playing in his first Grand Slam final in Melbourne, has lost all of his previous 12 matches against Nadal.
"The record is not what I'm looking at," BBC Sport Wawrinka quotes as saying. "I don't care. It's more about playing Rafa.
"He's the number one, the best player. His game is quite tough for me, especially with a one-handed backhand. But I did some good matches last year against him, close ones. I found a few things that I will try.
"Before, for me to beat [Novak] Djokovic was the same. I was losing 13, 14 times before that. I'm always trying and I always think that I can change all the statistics."
Wawrinka will climb to third in the ATP rankings if he wins the Australian Open.