England head coach Stuart Lancaster has dropped Owen Farrell to the bench in favour of Toby Flood for the side's second Test against South Africa in Johannesburg.
Flood will come in at number 10 with centre Jonathan Joseph receiving his first start for England, pushing Manu Tuilagi to inside in order to take over from the injured Brad Barritt.
"Owen has had a fantastic season and I am sure he will make a significant impact from the bench," said Lancaster. "However, Toby has waited patiently for his opportunity and the time is right to allow him the chance to demonstrate his experience and skills in what will be a very tough challenge."
David Strettle will also start on the wing, while Ben Foden will switch back to full-back following Mike Brown's exclusion with a thumb injury.
England: Foden, Ashton, Joseph, Tuilagi, Strettle, Flood, Youngs, Marler, Hartley, Cole, Botha, Parling, Johnson, Robshaw (c), Morgan.
Danielle Joynson
