England head coach Steve McNamara has named eight uncapped players in his 24-man squad for the upcoming International Series against France and New Zealand.
Uncapped John Bateman and Joe Burgess join teammate Williams, along with Warrington Wolves forward Ben Currie, Castleford Tigers half-back Luke Gale, and St George Illawarra Dragons forward Mike Cooper.
Wigan's Sean O'Loughlin will captain the side.
England will kick off the International Series against France at Leigh Sports Village on October 24.
England squad: John Bateman, Joe Burgess, Liam Farrell, Sean O'Loughlin (c), Matty Smith, George Williams (Wigan), Thomas Burgess (South Sydney Rabbitohs), Mike Cooper, Gareth Widdop (St George Illawarra), Leroy Cudjoe, Brett Ferres, Jermaine McGillvary (Huddersfield Giants), Ben Currie, Chris Hill, Ben Westwood (Warrington Wolves), Luke Gale (Castleford Tigers), James Graham (Canterbury Bulldogs), Ryan Hall, Zak Hardaker, Kallum Watkins (Leeds Rhinos), Josh Hodgson (Canberra Raiders), James Roby (St Helens), Sam Tomkins (NZ Warriors), Elliott Whitehead (Catalans Dragons).