The visitors are second in the A-League table and could move past Central Coast Mariners into first place with a win.
Sydney fumbled their chance to move ahead of Melbourne City into third place as they were held to a 1-1 draw by the Melbourne outfit last time out.
That was Sydney's fifth draw of the season, and this has been a major hindrance to their rise up the table.
Their poor display in front of goal is another factor, as they have scored the joint-fewest goals of the top six sides in the division.
However, a win on Sunday could see Steve Corica's men move into second place, as they have a stronger goal difference than the visitors.
Meanwhile, Adelaide United's charge to the summit of the A-League table resumed last week when they claimed a 3-1 win over Macarthur.
Carl Veart's men have now picked up 22 points from their last 27, and this run has seen them surge into second place in the league.
That rise has also been down to their impressive performances on home turf, where they boast the league's best record with six wins and one draw in eight games.
While victory could take Adelaide United to the top of the standings, they face an uphill battle when travelling to the Leichhardt Oval, where they have suffered defeat in their last four visits.
With three goals and one assist in his last three games, Sydney's attack will once again be led by the in-form Kosta Barbarouses.
Adelaide will be without the services of Spanish midfielder Javi Lopez, who is sidelined with a knee problem.
He is joined on the treatment table by Mohamed Toure, who picked up a hamstring injury in the 2-1 win over Newcastle Jets on March 5.
Sydney FC possible starting lineup:
Redmayne; King, McGowan, Wilkinson, Grant; Brattan, Baumjohann, Ninkovic, Retre; Barbarouses, Bobo
Adelaide United possible starting lineup:
Gauci; Strain, Elsey, Timotheou, Cavallo; Caletti, Juande; Halloran, Mauk, Goodwin; Juric
We say: Sydney FC 1-1 Adelaide United
Both sides come into this with a decent run of results and will be aiming to strengthen their position in the league standing. Adelaide United have managed just three wins on the road so far, and we expect they drop more points in this tie.