Both managers are dealing with an injury crisis at present, and here, Sports Mole rounds up all the latest team news for the two struggling sides.
Out: Phil Jagielka (suspended), John Egan (foot), Sander Berge (thigh), Jack O'Connell (knee), Jack Robinson (unspecified), Chris Basham (muscle), Jayden Bogle (leg), Jack Rodwell (unspecified)
Sports Mole's predicted XI: Ramsdale; Ampadu, Bryan, Lowe; Baldock, Norwood, Fleck, Lundstram, Stevens; McGoldrick, McBurnie
Out: Theo Walcott (thigh), Michael Obafemi (muscle), Oriol Romeu (ankle), William Smallbone (knee)
Doubtful: Takumi Minamino (hamstring), Kyle Walker-Peters (hamstring), Ibrahima Diallo (thigh), Moussa Djenepo (knock)
Sports Mole's predicted XI: McCarthy; Bednarek, Vestergaard, Salisu, Bertrand; Redmond, Armstrong, Ward-Prowse, Minamino; Ings, Adams
Watch the Sports Mole Football Shorts prediction for this game below: