Plymouth Argyle will be desperate to collect their first points of the League One season when they welcome Leyton Orient to Home Park on Tuesday.
As for the visitors, they will be looking to make it three league games without defeat after taking four points from their last two outings in the third tier.
Match preview
Plymouth are looking for an immediate return to the Championship after suffering relegation in a forgettable 2024-25 campaign.
However, former Watford boss Tom Cleverley has experienced a disappointing start to his tenure, having lost each of his opening three league games as Plymouth head coach.
The Pilgrims began the campaign with a 3-1 home defeat against Barnsley, before they failed to trouble the scorers in a 2-0 away loss against Bolton Wanderers.
Plymouth finally claimed their first win of the season in last week's EFL Cup clash against Queens Park Rangers, but they ultimately failed to build upon that 3-2 victory as they came out the wrong side of the same scoreline in Saturday's away meeting with Lincoln City.
Goals from Owen Oseni and Xavier Amaechi ultimately proved too little too late as the Pilgrims fell short in their quest to cancel out a three-goal deficit, ensuring that they enter the midweek round of fixtures as one of three League One team without a point to their name.
With Plymouth in need of inspiration, they may find it in the fact that they have won each of their previous three competitive home games against Leyton Orient.
Leyton Orient face the tough challenge of lifting themselves to go again after falling short in last season's playoff final against Charlton Athletic at Wembley.
The O's started their latest top-six bid with a disappointing 3-0 defeat to Huddersfield Town, before they got on the board with a 2-0 home win over Wigan Athletic.
After losing to Wycombe Wanderers in the EFL Cup, Richie Wellens's side looked set to fall to another defeat when they conceded two goals in Saturday's league meeting with Stockport County.
However, they showed great character to stage a second-half fightback, which saw Aaron Connolly net in the 57th minute, before Ollie O'Neill scored a dramatic stoppage-time equaliser to rescue a 2-2 draw.
They will now head on their travels for their first meeting with Plymouth since falling to a 2-0 defeat in the EFL Trophy in August 2023.
The O's will enter the midweek fixture with aspirations of claiming a head-to-head away win for the first time since February 2017.
Plymouth Argyle League One form:
Plymouth Argyle form (all competitions):
Leyton Orient League One form:
Leyton Orient form (all competitions):
Team News
Plymouth are expected to be without Conor Hazard, Julio Pleguezuelo, Jack MacKenzie, Freddie Issaka and Jamie Paterson.
Captain Joe Edwards is closing in on a return to fitness, but it remains to be seen whether he will be ready for Tuesday's fixture.
Defender Brendan Wiredu will serve a one-match suspension after being sent off for two bookable offences in the closing stages of the defeat to Lincoln.
As for the visitors, midfielder Zech Obiero is expected to be out for 10 to 12 weeks after he sustained a knee injury in last week's EFL cup defeat to Wycombe.
Tyreeq Bakinson came off the bench to provide the assist for O'Neill's equaliser at the weekend, and the former Plymouth midfielder will now be hoping to earn a starting spot for the midweek clash.
Connolly will continue to lead the line after opening his Leyton Orient account in Saturday's draw with Stockport.
Plymouth Argyle possible starting lineup:
Ashby-Hammond; Szucs, Galloway, Palsson, Sorinola; Boateng, Roberts; Amaechi, Watts, Mumba; Oseni
Leyton Orient possible starting lineup:
Simkin; James, Beckles, Happe, Adaramola; Jaiyesimi, Bakinson, El Mizouni; Koroma, O'Neill, Connolly
We say: Plymouth Argyle 2-2 Leyton Orient
Leyton Orient have lost their last three competitive games against Plymouth, but with their opponents struggling for confidence, we think that the visitors will do enough to leave Home Park with a point to show for their efforts.
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