Olympiacos and Marseille will both be looking to build on weekend victories in their respective leagues when the two sides lock horns at the Stadio Georgios Karaiskakis in the Champions League on Wednesday evening.
The hosts marched to a comfortable 4-0 triumph over Atromitos Athens on Saturday, while Marseille overcame Bordeaux 3-1 in Ligue 1 last time out.
Olympiacos made headlines last season when they sent Arsenal packing at the last-32 stage of the Europa League before succumbing to a 2-1 aggregate defeat to another Premier League side in Wolverhampton Wanderers in the round of 16.
Prior to their Europa League venture, the perennial Greek champions had finished third in their Champions League group behind Bayern Munich and Tottenham Hotspur - marking the fifth time in a row that Olympiacos had failed to advance to the knockout round of Europe's elite competition.
While Pedro Martins will be eyeing a first top-two finish in the group stage for Olympiacos since the 2013-14 campaign, a group including Marseille, Porto and Manchester City will pose enormous challenges for the Greek Super League champions, but Thrylos will be cautiously optimistic having started the new season in terrific fashion.
Martins's side have won three and drawn one in the 2020-21 Greek Super League and boast a stellar goal difference of +9 at this early stage - scoring 10 and conceding just one in the top division thus far - with Youssef El Arabi coming off the bench to bag a hat-trick in his side's 4-0 thrashing of Atromitos at the weekend.
Olympiacos were forced to go down the playoff path to secure a route into the Champions League group stage, and the Greek champions overcame Cypriot side Omomia 2-0 at home before a goalless stalemate a week later confirmed Olympiacos's qualification for Group C.
Meanwhile, Marseille were tasked with trying to end a run of 1-1 stalemates against a Bordeaux side who have become renowned for their defensive capabilities in the French top flight.
However, Les Girondins were swept aside by Marseille as Andre Villas-Boas saw his team storm to a 3-1 victory in gameweek seven - their first victory since their memorable derby triumph over Paris Saint-Germain last month.
Goals from Florian Thauvin, Jordan Amavi and an own goal from Pablo saw Marseille record their third league win of the season, and Marseille will endeavour to carry that momentum forward as they return to the big stage in Europe after a seven-year absence this week.
A resounding victory in the league is just what Villas-Boas needed before Marseille prepare to take to the pitch in Europe's elite competition for the first time since the 2013-14 campaign, in which the Ligue 1 side recorded zero points in a challenging group which included Arsenal, Napoli and Borussia Dortmund.
Olympiacos and Marseille last met in the group stage of the 2011-12 Champions League, with Les Olympiens enjoying a 1-0 victory in Greece before Olympiacos prevailed by the same scoreline at the Orange Velodrome.
Olympiacos Champions League form: WD
Olympiacos form (all competitions): WWWDDW
Marseille form (all competitions): WLDDDW
El Arabi - also the hero of the hour against Arsenal in the Europa League last season - is sure to start this one after netting three times off the bench for Olympiacos last time out.
With regards to Marseille, Dimitri Payet sat out the weekend victory over Bordeaux through suspension but is available here, meaning that Villas-Boas may switch back to his favoured 4-3-3 formation.
However, there may be a change up top for the visitors as Dario Benedetto was forced off with a twisted ankle on Saturday, meaning that Valere Germain could spearhead the Olympiens attack, although Villas-Boas hinted at playing Payet as a number nine after the win over Bordeaux.
Olympiacos possible starting lineup:
Sa; Rafinha, Ba, Cisse, Cholevas; M'Vila, Camara; Valbuena, Fortounis, Masouras; El Arabi
Marseille possible starting lineup:
Mandanda; Sakai, Gonzalez, Balerdi, Amavi; Kamara, Strootman, Sanson; Thauvin, Germain, Payet
We say: Olympiacos 2-2 Marseille
This is a difficult game to call between two sides who would do extremely well to pip City or Porto to the top two spots in Group C. Olympiacos and Marseille will both be full of confidence heading into this match following impressive victories at the weekend, but we cannot separate the two clubs and are ultimately backing a high-scoring draw on Wednesday evening.