Elsewhere, Chris Burke and Michail Antonio line up in midfield, while Michael Mancienne and Jack Hunt make their bow in defense alongside Danny Fox, who sealed a permanent switch to the City Ground in May.
Karl Darlow, who secured a move to Newcastle United this afternoon, will start in goal after being loaned back to the Reds for the season.
Meanwhile, Blackpool, who had just eight players on their books 12 days ago, have named just 15 players in their matchday squad after enduring a summer of turmoil.
In consequence of their off-the-field problems, manager Jose Riga names just four substitutes on the bench.
Nottingham Forest: Darlow; Harding, Fox, Mancienne, Hunt; Reid, Burke, Antonio, Cohen; Fryatt; Assombalonga
Blackpool: Lewis; McMahon, Clarke, Daniels, Perkins; Lundstram, Mellis, Cywka, Orlandi; Zenjov, Delfouneso