The 18-year-old was an unused substitute in Friday's 2-0 victory over Malta and comes in for Kieran Trippier, who pulled out of the squad over the weekend for personal reasons.
At the tip of the attack, Aston Villa's Ollie Watkins has been given the nod over Harry Kane, while Jack Grealish and Bukayo Saka replace Marcus Rashford - who is fit enough for a place on the bench - and Conor Gallagher.
England - who are already confirmed to have qualified for next year's tournament as Group C winners - will be seeded in Pot 1 for the Euro 2024 group-stage draw with at least a point in Skopje.
North Macedonia: Dimitrievski; Musliu, Serafimov, Manev; Dimoski, Atanasov, Alimi, Alioski; Miovski, Bardhi, Elmas
Subs: Aleksovski, Shiskovski, Iljazovski, Ashkovski, Ademi, Churlinov, Mitrovski, Kostadinov, Elezi, Ristovski, Daci, Todoroski
England: Pickford; Walker, Guehi, Maguire, Lewis; Alexander-Arnold, Rice; Saka, Foden, Grealish; Watkins
Subs: Johnstone, Ramsdale, Tomori, Henderson, Phillips, Gallagher, Konsa, Rashford, Palmer, Kane